Inovelab

Understanding the innovation pattern of medium and large size brazilian pharmaceutical companies

Product innovation or business innovation? What should companies follow? Based on products and business innovation concepts and Concurrent Engineering (CE), Integrated Product Development (IPD), Stage Gates and Product Based Business (PBB), this paper presents an innovation reference model developed for Brazilian pharmaceutical companies. Qualitative research was conducted in six pharmaceutical companies in order to better understand their scenario and to compare their reality of innovation processes. The focus of this paper is to understand how thesecompanies identify innovation opportunities (in the pre-development phase) and what constraints they face to implement them. Some comparisons are made among them and some recommendations concerning the innovation process are presented.

The brazilian Condor S.A. Indústria Química developed a flare parachute, capable to help the Navy in nocturnal searches in the sea or the policy to face dealers in mounts. The part illuminates the target for 30 seconds. The company waits authorization of the Army to initiate sells.

Condor is the leader and pioneer in Latin America in manufacturing Non-lethal Equipment and high-tech Pyrotechnicals for riots, military signaling and salvaging and it has a privileged position in the world ranking.

Located in Rio de Janeiro, in the municipality of Nova Iguaçú, its factory is installed in a total surface area of approximately 1,000.000 (one million) square meters, next to the biological resort of Tinguá, with 26 thousand hectares, which is the largest resort of the Atlantic Rain Forest of the State of Rio de Janeiro. Condor follows a permanent policy of nature protection by allocating 40% of its total area to preserve the native forest, the water springs, the flora and the fauna, thus turning the factory environment into an ecological island, perfectly fine-tuned with the “Non-Lethal” concept of respecting life and citizenship.

NANOX TECNOLOGIA S/A is a company that develops nanotechnology solutions. Its aim is to develop and produce surface treatment solutions, oxide synthesis and nanometric metals, aiming at improving surface properties. NANOX®’s coatings can be applied to a number of different kindsof surfaces.

The company is a spin-off from the Federal University of São Carlos (UFSCar), in the State of São Paulo. It originated at UFSCar’s CMDMC/LIEC, the country’s leading nanotech laboratory, with which it maintains active research and cooperation agreements.

The NANOX® technology for synthesizing nanomaterials has grown from a bottom-up method and more specifically from chemical synthesis methods.

Using its own technologies, NANOX® produces nanometric compounds with a controlled particle size and distribution, elevated homogeneity, controlled stoichiometry, at a low cost and on an industrial scale. Further, these processes allow materials with different characteristics to be made compatible, i.e. polar materials can be chemically transformed so as to incorporate or react with apolar materials, bringing about significant changes to the materials’ properties. Thus, NANOX® creates atomic-scale materials, modeling the properties of the materials and surfaces, and can produce a range of amorphous and crystalline materials, including simple and mixed metal oxides, coatings, nanocompounds and materials for clean energy.

Nanox Tecnologia
Rua Jose Missali, 820 - Planalto Paraíso
CEP 135602-060 - Sao Carlos - SP - Brasil
Phone: +55 16 3364-2235
Website: www.nanox.com.br

CIETEC – The Technology–Based Business Incubator Center - was inaugurated in April of 1998, in São Paulo, within a partnering association with SCTDE-SP - The Science, Technology and Economic Development Secretary of the State of São Paulo; SEBRAE-SP - The Brazilian Support Service for Micro and Small Businesses; USP – São Paulo University; CNEN - The National Commission of Nuclear Energy - through IPEN - The Nuclear and Energy Research Institute , and IPT - The Institute of Technological Research of the State of São Paulo , entities which compose Cietec’s Board of Directors. Later, MCT - the Ministry of Science and Technology - was incorporated to the Board

Cietec’s mission is to promote the development of Brazilian technology and science, by encouraging its members to turn knowledge into innovative and competitive products and services.

In order to do that, CIETEC lies ahead of a national development strategy to encourage entrepreneurship, enhance quality of life and position the country as a creating and exporting base of innovative technologies in the various fields of knowledge.

CIETEC provides its small and micro companies with tools which will increase their survival and competitiveness, offering these technology-based companies the excellence of its infra-structure and human resources.

Amid the differentials that make CIETEC one of the most important incubator centers in the Country, the primary one is its privileged location. Based in Cidade Universitária de São Paulo, CIETEC’S tenant companies have access to the laboratories of IPEN, IPT and USP, fundamental to ensure the quality of their projects.

For being a connection link between education and research institutions, government bodies and private organizations, it is Cietec’s policy to constantly improve exchange of information and support service throughout all the networking made up by entrepreneurs, investors, researchers, scientists, journalists, consultants, students, professors and company owners.

CIETEC
Av. Prof° Lineu Prestes, 2242 - Sao Paulo
Cidade Universitária - Butantã - CEP 05708-000
Phone: (11) 3039.8300
Website: http://www.cietec.org.br/

Pam Membranas Seletivas is growing for uniting environment protection to cost reduction. The company, who was born in Federal University of Rio de Janeiro (UFRJ) Incubator, manufactures microfiltration membranes to treat effluent and, thus, to reuse water. It finished to deliver two microfiltration units, one for Petrobras and another one for Dupont. Petrobras will use the equipment in the oil field of Fazenda Belém, in Ceará, to separate water from oil.

- Petrobra's wants to use this recicled and clean water to irrigate a mamona plantation for production of biodiesel - says Ronaldo Nóbrega, Pam Membrana's director, a retired Chemistry Engineering UFRJ Professor who developed the technology with his post-graduate students

Dupont, in Uberaba (MG), uses the filter to recoup a harmful pigment from the nature allowing its recycling and reuse. Pam Mambrana has also made tests in a brewery of São Paulo. And negotiates with the Votorantim Cellulose and Paper the implementation of its first filter of great dimension:

- We wait to close the year with bigger invoicing five times that of 2006, that it was of US$ 125 a thousand.

Pam Membrana has also won two innovation funding projects from the Brazilian innovation agency - FINEP and from the State of Rio de Janeiro Science and Technology Agency - FAPERJ to improve its microfiltration technology.

Pam-Membranas Seletivas
COPPE-UFRJ, Cidade Universitária - Rio de Janeiro
Caixa Postal 68568 - CEP: 21941-972
Phone: +5521-2590-3428
Fax: +5521-2590-4334
E-mail: pam-membranas@inc.coppe.ufrj.br

This year Vitrogen completes eight years of commercial performance in Brazil commemorating one historical mark: more than 360 a thousand bovine embryos produced by In vitro fertilisation (IVF). Of this volume 305 a thousand embryos had been transferred to receiving cows, an average of 40% of confirmed pregnancies.

Beyond this production increment of bovine embryos in domestic territory, Vitrogen has since 2003 also expanded its action in other South-american countries. Currently the company possesss laboratories in Colombia, Uruguay and Venezuela and Mexico. According to Yeda Watanabe, one of the partners of the Vitrogen, these three countries had already produced more than 50 a thousand embryos. The forecast is that in 2007 Vitrogen must produce between 6 and 10 a thousand pregnancies by IVF only in Colombia. In Brazil four units, installed in Cravinhos/SP, Uberaba/MG, Field Grande/MS and Morrinhos/GO (this in partnership with the Samvet Embryos) are in production.

The Vitrogen also is pioneering in the commercial application of the of bovines, goat and ovinos cloning and is searching partnerships for projects of national and international expansion. Vitrogen develops research projects and it offers other services in biotechnologies for animal reproduction.

Vitrogen
Rua Sete de Setembro, 601 - Alto das Acácias
Cep 14।140-000 - Cravinhos/SP
Phone: 55(16) 3951-9255
info@vitrogen.com.br

The Brazilian Space Agency (Agência Espacial Brasileira) is the civilian authority in Brazil that is in charge of the country's burgeoning space program. It operates a rocket launch site at Alcântara. Its location near the equator means that less energy is required to launch into space.

The Brazilian Space Agency is the heir to Brazil's space program. Previously, the program had been under the control of the Brazilian military. Because of pressure from the United States over the possible military application of its space program, the program was transferred into civilian control on 10 February 1994.

It suffered a major setback in 2003, when a rocket explosion killed 21 technicians. The first successful rocket was launched on October 23, 2004; it was a VSV-30, or Brazilian Exploration Vehicle, launched on a sub-orbital mission.

A joint venture company for rockets and satellites, established by Brazil and Ukraine, should begin operating this year. The partnership is aimed at launching rockets and satellites from the Alcântara Base, in the northeastern Brazilian state of Maranhão. The first launch should take place by 2009, according to the AEB, which completed 13 years of existence on February 10th, 2007.

Brazil will make available its launch area in Alcântara and the Ukrainians will provide the launching technology developed in Ukraine.

The company is expected to profit the equivalent of roughly 10% of the global satellite launching market, worth US$ 10 billion, over the next eight years, since countries that own satellites will be able to pay to use the base and the launching technology.

Brazilian oil giant Petrobras, Ultra group, in the gas, chemical and transport sector, and petrochemical company Braskem signed an agreement to acquire the businesses of Ipiranga group. The value of the operation will be US$ 4 billion. Ipiranga operates in the oil refining, petrochemical and fuel distribution sectors.

Petroleo Brasileiro S.A. (Petrobras) is a wholly owned enterprise of the Brazilian Government, which is engaged in the energy sector. Petrobras is divided into four business areas: Exploration and Production, Downstream, Gas & Energy and International, and two support functions, which are Finance and Services. The Company has over 100 production platforms, 16 refineries, 30,000 kilometers of ducts and more than 6,000 gas stations. Petrobras is also present in other countries, namely Angola, Argentina, Bolivia, Colombia, Nigeria, and the United States, as well as having the support of its overseas offices in New York (ESNOR), and Japan (ESJAP). Brazilian oil company Petrobras has signed an agreement with the Ministry of Energy and Mineral Resources of Jordan that forecasts the viability study for the use of the Brazilian company's technology in the production of oil in the Arab country. The technology is Petrosix, for the production of schist oil, and it should be used in the AUG block, in the Attarat field, in the Arab country.

Braskem S.A. (Braskem) is an integrated petrochemical cracker and thermoplastics producer in Brazil. The Company produces a portfolio of petrochemical products, and focuses on polyethylene, polypropylene and polyvinyl chloride (PVC). Braskem operates through four business units: Basic Petrochemicals, Polyolefins, Vinyls and Business Development. The Basic Petrochemicals Unit includes the Company's basic petrochemical production activities, and supply of electricity, steam and compressed air to second-generation producers. The Polyolefins Unit encompasses activities related to the production of polyethylene and polypropylene. The Vinyls Unit is engaged in the production of PVC, caustic soda and chlorine. The Business Development Unit is engaged in activities related to the production of other second-generation petrochemical products. On April 6, 2006, the Company acquired all of the common and preferred shares of Politeno Industria e Comercio S.A.

Ultrapar Participações S.A. (Ultra Group)one of Brazil's most solid conglomerates। It unites three different companies, each with a prominent position in its own segment: Ultragaz, the leader in Brazil's distribution market for Liquid Petroleum Gas (LPG), with a 24% market share; Oxiteno, the largest producer of specialty chemicals in Brazil and the only manufacturer of ethylene oxide and its main derivatives in Mercosur area (comprising Brazil, Argentina, Paraguay and Uruguay); and Ultracargo, a leading provider of integrated road transport, storage and handling services for chemicals and fuels.

Petrobras will take over the Ipiranga distribution network in the North, Northeast and Midwest, and will have up to five years to use the Ipiranga brand, after which it will have to be replaced for the Petrobras Distribuidora brand। Braskem will manage 60% of the assets of Ipiranga Group in the petrochemical sector. Ultra will have the Ipiranga fuel distribution network in the South and Southeast of the country, and will continue running it under the Ipiranga brand. Petrobras will keep the other 40% of the Ipiranga group petrochemical activities.

The Ipiranga Refinery, in the southernmost Brazilian state of Rio Grande do Sul, will be equally controlled by Petrobras, Ultra Group and Braskem, who agree to proceed with the activities.

Brazilian president Luiz Inácio Lula da Silva signed a decree today (8) outlining a development policy for the biotechnology industry in the country implementing a national program to become the global leader in biotechnology in 10 to 15 years. The country's biodiversity places Brazil in an advantageous position compared to other countries.

According to the Brazilian Ministry of Development, Industry and Foreign Trade, there are currently 1,700 groups in the public, academic and private sectors working in the biotechnology sector in Brazil. The national program will manage and provide support to these activities, as well as facilitate corporate access to research results.

Already in 2007, according to information provided by the minister of Development, Luiz Fernando Furlan, US$ 479.5 million in public funds will be available for biotechnology research in the country. The money will be provided by the Brazilian Development Bank (BNDES) and by sector funds already managed by the National Innovation Agency (Finep), which are linked to the ministries and consist of tax revenues.

The plan was devised through debates between the private and public sectors, and will receive support from five ministries, all of which are somehow related to the area: Health, Development, Science and Technology, Agriculture and Environment. The goal is to encourage biotechnological applications in five different fields: health, food security, animal health, industrial products and environmental quality.

A national committee will be established, including representatives of the five ministries and of the academic sector, to monitor the development of the program. Biotechnology should foster production, and consequently employment in the country, in addition to opening new doors to the foreign market.

In fact, Brazilian biotech research has already shown promising results. The minister cited as examples the work of the Amazon Biotechnology Center - CBA, which developed natural colouring products for food and cosmetics, and the work of a factory, in the northeastern Brazilian state of Bahia, which produces sterile flies designed to eradicate fruit flies; these sterile flies are now being exported.

Brazilian biotechnology also led to the creation of new strains of sugar cane and soy, capable of thriving both in the country's dry and more humid areas, not to mention ethanol production, another result of biotech. Brazil is currently the leading ethanol producer in the world.

The program launched today should contribute to lessen Brazilian imports of medications, and help the country become an exporter of certain medical products. "In imports of vaccines against rabies alone, Brazil spends US$ 38.8 million a year," said Furlan.

The Ministry of Health already provides support to several programs aimed at innovation in medication. One such program is turned to the manufacturing of pharmaceuticals using marine microalgae. Another program specializes in developing medication to treat neglected diseases, such as malaria. This type of work, as well as biotech work in the agricultural and the industrial sectors, should get a boost from the new government plan.

The Brazilian Association of Biotechnology Companies (Abrabi) estimates the annual revenue of the biotechnology sector in the country to be between US$ 2.5 billion and US$ 4.3 billion. Of the 28,000 job positions created, 84% are in the micro and small businesses.

Foreign resources and participation in biotechnological development is also welcome, according to the consultant for biotechnology, pharmaceuticals and medication at the Brazilian Agency for Industrial Development (ABDI), Adriana Diaféria. Adriana explained that Brazil wants to show how advanced it is in the field, thus encouraging exchange with other countries.

Companies with 100% Brazilian capital are entering in the automotive market. That is the case with company Tecnologia Automotiva Catarinense - TAC, from the southeastern Brazilian state of Santa Catarina, which is developing jeep Stark, which means "strength" in German, previously know as Project A4.

The 4-wheel-drive jeep of futuristic lines is equipped with a Volkswagen 1.8 dual fuel engine, i.e., which operates both on petrol and alcohol. "This is a differential in the 4-wheel-drive vehicle sector, where the vehicles are generally run on petrol or diesel," stated the company's administrative director, Luiz Alberto Cavalheiro.

The National Agency for Financing Studies and Researches - Finep has launched the book "Innovative Brazil, the Enterprising Challenge", where success stories of the 40 more innovative brazilian companies are listed. Companies like Petrobras, Embraer, Braskem, Pipeway, Troller, Embrapa, Lupatech, Weg, Polymar, Nuteral and Modulo Security are among others.

Modulo Security, for instance, is the brazilian information security company. At the book you can learn about the history of the three partners that started the company after left the software engineering course at Federal University of Rio de Janeiro - UFRJ and how Modulo was transformed into the market leader of its sector. With more than 4 thousand national and international projects implanted, many of them innovative ones as the security of the Brazilian Voting Machines and the transmission of the income tax through the InterNet. Modulo was the first information security company of the world to get the ISO 27001 certification, first world-wide norm of information security.

Founded in '94 by three friends, two of wich are partners to this day, with the intention of having a good time and maybe some work, Lobo presents itself as a design and animation studio. The team of artisans leaded by Creative Director Mateus Santos seeks to employ the full extent of its capabilities to the craft, with the constant objective of doing unique work every time around.

Represented worldwide by The Ebeling Group, and teamed up with major 3D and post-production company Vector Zero, Lobo has grown quite a bit since the early days, but being aimed towards quality more than quantity, the team has now reached a solid set up. Designers, animatiors, illustrators, editors, plus a writer and a sound designer, all coming from veried backgrounds, compose the current team. This provides Lobo with a strong foundation for a broad range of projects.

From TV packages for Germany's Viva Networks, to the far out concepts and graphics for Diesel, Lobo's clients so far include Panasonic, Boomerang Channel, Gessy-Lever, Toyota, Sony Playstation, Anime Channel, Subaru, Cartoon Network, OLN, CMT, AMC, McCann Erickson, Kessels Kramer, Ogilvy & Matter Worldwide, Saatchi & Saatchi, BBDO, MTV and Disney.
Lobo's worldwide recent media attention includes reviews and interviews on magazines and books such as Creativity, Creative Review, Desing is Kinky, Die Gestalten, Etapes, How, ICG, Plus 81 and XFuns.

Lobo
Phone: 55 11 3709.2222
email: info@lobo.cx
Site: http://www.lobo.cx

The helmet adapter is one of the company’s top-of-the-line products. It is characterized by especially innovative features such as a lever and bending system, using torsion springs with a spin gauged to move the earplugs backwards. It also has a smaller amount of parts than its competitors, and uses simplified tooling. It can be adapted to any helmet brand. It is injected in ABS and receives a fiberglass load to cope with the wear and tear. With less movements and adjustments, users can remove and put the earplugs on intuitively, which contributes to improve their work conditions. The product was developed in Brazil with technical, functional and formal aspects that compete in equal conditions with imported products.
Manufacturer:
Bells Ind. e Com. de Plásticos Ltda
Pinhais, Brazil
http://www.bells.ind.br

Design:
Mega Box Design S/S LtdaAguilar Selhorst Jr, Felipe Locatelli, Nelson Kuster Jr
Quatro Barras, Brazil
http://www.megaboxdesign.com.br/

Since the 70s, environmental movements have discussed the impact of technological advance upon the planet ecosystem. With notions such as environmental impacts and risks in mind, environmental sociology has pointed out many effects of modern technologies on environment, mostly in a technological phobic manner and a defensive way. From the perspective of innovation, environment challenges are pure fuel to propel new different technologies. Instead of focusing on specific technologies and immediate effects, innovation provides a broader and systemic view on technological practices.

The substitution of CFC on chemistry industries and consummer goods in Brazil is a good example. The importation of gas CFC and the use of herbicide bromide of metila, two of the main substances that destroy the ozone layer, are forbidden in Brazil since the first day of 2007 by the Brazilian National Environment Council (Conama).

Currently, the CFC survives basically in old equipment, refrigerators, residential and automotive air-conditional equipment. The CFC alone only leaves the industrial plant, today, in the cases of "essential uses", as in the bomblet used in the treatment of the asthma. It is an exception in the Montreal protocol, but its use is restricted and can finish for complete, therefore a study government foresees the substitution to it of the CFC of the bomblets for another product researched in the program of Elimination of the Production and Consumption of the Substances that Destroy the Ozone Layer. The Program counts on financial resources of Protocol Multilateral Fund, that, until 2010, will invest USS 26,5 million in brazilian system of innovation.

The CFC of old equipment, as what it puts into motion refrigerators manufactured before 2000 (the posterior ones does not contain CFC), the call "cooling gas", will be recicled to keep in operation old equipment. With resources of Multilateral Fund, a Central office of Regeneration (bank of supply of the gas) was mounted in São Paulo. In 2007, another one will be opened, in Rio de Janeiro. One program of training of "refrigeristas" prepares low-income people who work in the collect of the CFC in refrigerators. Instead of liberating the gas for the atmosphere, them they direct to a regeneration central office.

Such policies are the building blocks of democratic and decentralized social and technological networks and efficient and multiple innovation environments represent today essential conditions for environmentalism.

O Boticário was created in 1977 as a small prescription drugstore in the city of Curitiba, capital of the state of Paraná, in southern Brazil. Today the company is the world’s largest perfumery and cosmetics franchising network. It has 2,114 stores in Brazil, 52 in Portugal, 4 stores in Mexico, 5 stores and 6 points of sales in Bolivia, 2 in Peru, and 2 in Paraguay, and its products are marketed in 438 points of sale in Japan.

O Boticário is perceived by its customers as a company that creates and distributes products that express sensitivity, harmony, and beauty; as a company that is a reference in innovation and high quality, and whose actions translate its absolute respect for the environment.

O Boticário’s product lines consist of approximately 480 items, divided into the following categories: body care, facial care, sun care, makeup, deodorizing colognes, deodorants, soaps and shampoos. All of them developed with the most advanced production and research techniques.

In addition to traditional ingredients such as almond oil, chamomile, eucalyptus, and grape, O Boticário consistently invests in new active ingredients research so that it can go on offering unique products. Amazonian plants such as assai, cupuaçu, carnaúba, guaraná, cashew, and passion flower; gums extracted from algae and vegetal extracts, such as arnica, and urucum are among the active ingredients present in the brand’s products.

O Boticário is a modern company, in synchrony with international market trends, and greatly concerned with the quality of the products it manufactures and customer well-being. By means of regular domestic and international surveys, the company has succeeded in developing world-class products, be it through their innovative packaging or through the use of first-class raw-materials, using the most advanced technology in packaging, formulations, and design.

O Boticário’s industrial and administrative complex has 34.4 thousand square meters of floor space in the city of São José dos Pinhais in the Curitiba Metropolitan Area. It employs 1,300 people and creates approximately 10 thousand jobs through its franchising network. O Boticário’s first manufacturing plant was inaugurated in 1982, with just 1 thousand square meters of floor space. Then it employed 27 people who worked to manufacture about 400 thousand items a year. O Boticário’s current production exceeds 59 million units.

In 1990, the O Boticario Nature Conservancy Foundation became a landmark in terms of support to conservationist projects, and is widely recognized abroad. UNESCO declared the Salto Morato Natural Reserve a natural heritage site, in 1999.

The Science and Engineering Brazilian Fair - FEBRACE comes fulfilling an important social paper stimulating the creativity and the reflection in students of the basic education through the development of sciences and engineering projects. The FEBRACE means 5 years discovering new talents and stimulating the research culture, innovation and entrepreneurship in Brazil.

The FEBRACE history is composed of pupils, professors, parents and schools that together show to the Brazilian society that they learn to learn, that they can want and that they can do.

The FEBRACE objectives are: - to stimulate new vocations in Sciences and Engineering through the development of creative and innovative projects; - to approach the public and private schools of the Universities, being created chances of spontaneous interaction between the students and professors of the schools with the university community (students, professors, employees), for one better understanding of the papers of the Universities in Education, Research, Culture and Extension.

The FEBRACE is a fair affiliated to Intel ISEF - International Fair of Sciences and Engineering - carried through annually in May in U.S.A. in different cities of the country. It is the biggest fair for students who had still not arrived at the university level.

Headquarter in Parobe, Rio Grande do Sul, 80 kilometres from the capital of the Southern State, Porto Alegre. Calçados Azaleia has three main production units at Rio Grande do Sul, Bahia and Sergipe, besides that Azaleia has trade representatives in Latin American countries, USA and Europe and four commercial units at Unites States, Chile, Colombia and Peru. The company exports 18% of its production to more than 80 countries and it is estabilished in more than 15.000 stores in Brazil and other 3.000 spread all over the world. On the women´s market, the company presents the brands Azaléia, Dijean and Funny. On the sportswear segment, it works with the brands Olympikus (leader in Brazil), Asics, through an agreement made with the Asics Tiger Corporation, and finally, with the brand Opanka.

Nowadays the brazilian shoe industry is suffering a strong competition from asiatic countries. With products 40% more cheaper, countries as China, Vietnam and Malasia, influence brazilian companies to search for alternatives to mantain the marketshare in the foreign. Research new designs, materials and techniques to improve the quality and aggregate value of its products are the policies of Azaleia in 2007.

Azaleia has earned from the Brazilian Innovation Agency - Finep (Research and Projects Financing) the amount of US$ 13 million to finance the R&D in the manufacture of recyclable sandals and tennis with the use of new polimers and bioplastics, as Luciano Sfoggia, finance director of Azaleia says "the manufacture of recyclable products goes within our environmental responsability", an important theme to all the company.

Calçados Azaléia S.A.
Rua Dr. Legendre nº 34 – Centro
CEP: 95630-000
Parobé – RS
Phone: (+5551) 3543. 1000
Site: http://www.azaleia.com.br